雜志介紹

Mutation Research-fundamental And Molecular Mechanisms Of Mutagenesis雜志介紹

《Mutation Research-fundamental And Molecular Mechanisms Of Mutagenesis》是一本以English為主的未開放獲取國(guó)際優(yōu)秀期刊，中文名稱突變研究-突變發(fā)生的基本和分子機(jī)制，本刊主要出版、報(bào)道醫(yī)學(xué)-BIOTECHNOLOGY & APPLIED MICROBIOLOGY領(lǐng)域的研究動(dòng)態(tài)以及在該領(lǐng)域取得的各方面的經(jīng)驗(yàn)和科研成果，介紹該領(lǐng)域有關(guān)本專業(yè)的最新進(jìn)展，探討行業(yè)發(fā)展的思路和方法，以促進(jìn)學(xué)術(shù)信息交流，提高行業(yè)發(fā)展。該刊已被國(guó)際權(quán)威數(shù)據(jù)庫(kù)SCIE收錄，為該領(lǐng)域相關(guān)學(xué)科的發(fā)展起到了良好的推動(dòng)作用，也得到了本專業(yè)人員的廣泛認(rèn)可。該刊最新影響因子為1.5，最新CiteScore 指數(shù)為4.9。

本刊近期中國(guó)學(xué)者發(fā)表的論文主要有：

• High concentration of sugars is genotoxic to folate-deficient cells

  Author: Xihan Guo, Xueqin Dai, Juan Ni, Neng Cao, Guofang Yang, Jinglun Xue, Xu Wang

• Mutation analysis of ZP1, ZP2, ZP3 and ZP4 genes in 152 Han Chinese samples with ovarian endometriosis

  Author: Yang Zou, Jiang-Yan Zhou, Jiu-Bai Guo, Zi-Yu Zhang, Yong Luo, Fa-Ying Liu, Huang Huang, Feng Wang, Ming He, Li-Qun Wang, Ou-Ping Huang

• Is level of acetylation directly correlated to radiation sensitivity of cancer cell?

  Author: Fengqiu Zhang, Zhu Chen, Changsheng Shao, Qing Huang

• p.Val19Glyfs*21 and p.Leu228* variants in the survival of motor neuron 1 trigger nonsense-mediated mRNA decay causing the SMN1 PTC+ transcripts degradation

  Author: Yu-jin Qu, Lin Ge, Jin-li Bai, Yan-yan Cao, Yu-wei Jin, Hong Wang, Lan Yang, Fang Song

英文介紹

Mutation Research-fundamental And Molecular Mechanisms Of Mutagenesis雜志英文介紹

Mutation Research (MR) provides a platform for publishing all aspects of DNA mutations and epimutations, from basic evolutionary aspects to translational applications in genetic and epigenetic diagnostics and therapy. Mutations are defined as all possible alterations in DNA sequence and sequence organization, from point mutations to genome structural variation, chromosomal aberrations and aneuploidy. Epimutations are defined as alterations in the epigenome, i.e., changes in DNA methylation, histone modification and small regulatory RNAs.

MR publishes articles in the following areas:

Of special interest are basic mechanisms through which DNA damage and mutations impact development and differentiation, stem cell biology and cell fate in general, including various forms of cell death and cellular senescence.

The study of genome instability in human molecular epidemiology and in relation to complex phenotypes, such as human disease, is considered a growing area of importance.

Mechanisms of (epi)mutation induction, for example, during DNA repair, replication or recombination; novel methods of (epi)mutation detection, with a focus on ultra-high-throughput sequencing.

Landscape of somatic mutations and epimutations in cancer and aging.

Role of de novo mutations in human disease and aging; mutations in population genomics.

Interactions between mutations and epimutations.

The role of epimutations in chromatin structure and function.

Mitochondrial DNA mutations and their consequences in terms of human disease and aging.

Novel ways to generate mutations and epimutations in cell lines and animal models.